Ostarine (MK-2866)

Ostarine (MK-2866) is a popular Selective Androgen Receptor Modulator (SARM), used in athletes and bodybuilding, to increase the strength and mass of lean muscles.

Ostarine is capable of stimulating androgen receptors, steroid hormone receptors, and also mimicking testosterone.

The side effects of this SARM is limited, because it targets specific tissues of the body. Such tissues include the bones and muscles. This means that, by taking SARM, you don’t have to worry about an increase in estrogen level or the suppression of the testosterone level.

The intake of MK-2866 gives favourable results and it’s well-known for improving appearance and enhancing performance in athletes and bodybuilders. Based on how it works, it is safer than steroids and other SARMs, although it’s yet to be approved for use by human.

Ostarine was specifically developed to get rid of the diseases of the muscle, and prevent muscle loss, but they’re still under this clinical research to establish that fact.

Preclinical and clinical Phase I and II trials have demonstrated that enobosarm is able to improve lean body mass and improve certain measures of function and power. Full release of data from Phase III trials POWER1 and POWER2 is pending but preliminary results suggest significant improvement in lean body mass.

Future Oncol. 2014 Feb;10(2):187-94. doi: 10.2217/fon.13.273.

If this clinical research confirms its benefit and risk ratio, it may be approved for use. However, it is illegal for use in professional sports, and was banned by the World Anti-Doping Agency, included in the Prohibited list under the SI Anabolic Agent category in 2008.

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How It Works

The action of male sex hormones known as androgens is more than building muscles or increase in the skeletal muscle mass of the body. If steroids are used to stimulate the sensors meant for androgens, there are likely some side effects accompanying them.

SARMs concentrate on specific areas of the body such as the muscles, and aids in increasing the anabolic processes without affecting reproductive organs. The structure of MK-2866 offers few advantages amongst other synthesized SARMs, and clinical studies are still ongoing to discover new and more effective drugs for muscle building.

When Ostarine was tested on an animal known as mice, it was very effective just like dihydrotestosterone and androgen, to restore the mass of muscles in the pelvic floor which are rich in AR (androgen receptors). This SARM can activate stem cells which helps in muscle regeneration and remodelling.

Treatment of an ovariectomized mouse model with SARMs resulted in an increase in pelvic floor muscles, which may translate to an improvement of symptoms associated with SUI and serves as the basis for evaluating their clinical use.

J. Cell. Biochem. 118: 640-646, 2017.

With MK-2866, cells in your connective tissues can be stimulated for quick recovery from injuries to muscles. Also, the intake of Ostabolic may lead to a boost in the strength and growth of muscles by increasing the activity of IGF-1 (Insulin-like growth factor 1 gene).

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Benefits of Ostarine

The benefits of using Ostarine depends on:

  • Your longterm goals
  • How frequent you lift
  • Your nutrition
  • Your usage with other SARMs.

If you’ve a good diet with steady workouts put in place while using MK-2866, these are the expected results.

1. Lean Muscle Mass

If you’ve a good diet with routine workouts, you may gain up to 11lbs. of lean muscle mass, although this achievement may vary depending on the individual. Some people may gain as much as 15lbs. or as low as 5lbs. but a safe range is 6-8lbs.

2. Muscle/Bone Healing

Ostarine gives fast recovery from muscle soreness and bone healing even in small doses. It gives real strength to bodybuilders and athletes, so that they can stretch beyond their normal ability when they’re involved in compound movements such as bench presses and squats.

3. Loss of Fat

Muscle loss is a major turn-off to cutting cycles for bodybuilders. Intake of Ostarine prevents the breakdown of muscles while burning fats. This is where bodybuilders benefit most from Ostarine.

4. Healthy Heart

Ostarine is important for people suffering from heart diseases or related ailments. These set of people often encounter weight loss and muscle wasting.

In an experiment conducted on about 121 healthy elderly people, a daily intake of 1-3mg of enobosarm, reduced lipids such as HDL cholesterol, total cholesterol, as well as triglycerides in the blood, to give a healthy lipid level which helps prevent diseases of the heart.

In this study, enobosarm also helps to lower the blood glucose level and improve insulin resistance in the body.

Other benefits are:

  • It increases endurance in lifting and also boost strength
  • Has a very high anabolic impact on the body
  • Gives prolonged stamina for training
  • Helps to burn more calories than consumed
  • Increases the retention of nitrogen in the body.
ostarine results (before and after)

How To Use It

There are several ways in which Ostarine could be used.

Cycle Length

MK-2866 can be used alone in a cycle of 12 weeks by men, and 6-8 weeks by women, or used with other SARMs such as MK677 and LGD-4033.

Dosage for Men

15-25mg dose of Ostarine is recommended for men at the cutting phase for 8-12 weeks. This should be taken at about 30-40min before workouts and after meals. This same dosage is also recommended for men at the bulking phase.

Dosage for Women

5-10mg dose of MK-2866 is recommended for women, to be taken 30-40 minutes before workouts and after meals. This should be in a 6-8 weeks cycle.

Product Half-life

MK-2866 has a very long half-life of 24 hours, so it’s not necessary to divide your dose.

Side Effects of Ostarine

SARMs like Ostarine does not affect all the cellular receptors of the body. So, its side effect is not as severe as that of steroids.

Some of the side effects experienced when this powerful compound is ingested include:

  • Mild suppression in the production of testosterone at higher doses of Ostarine.
  • Swollen nipples is experienced on few people due to an increased blood estradiol. This happens to users sensitive to estrogen.
  • It causes headache and back pain on new users.
  • Some users may experience erection difficulties, baldness, reduced strength, joint pain, and skin changes due to higher doses of Ostarine.

Best Place To Buy Ostarine

Most SARMs are sold in the black market, but we advice you to look for reputable and trusted sellers of this compound such as SARMS1.

You may be at great risk if you don’t buy from genuine sellers, because you may not know the junks you’re ingesting into your body.


MK-2866 is a very effective and mild SARM with few side effects, and from clinical studies, it’s known to be one of the safest and most used SARMs.

If you need a SARM with little or no side effects, but gives good results, then Ostarine should make a great choice.

Ostarine Review
  • Lean Muscle Mass
  • Muscle/Bone Healing
  • Loss of Fat
  • Healthy Heart

Total Comments (1)

  1. Al June 22, 2019